Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.30 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293716 | 0.91 | RAB9A (0.31) | RAB9ASMARCA2SMARCA4PBRM1 | |
| SCHEMBL31293898 | 0.89 | MAPT (0.33) | MAPTTACR3THRBRAB9ASMARCA2 | |
| SCHEMBL26685076 | 0.87 | MAPT (0.34) | MAPTTACR3THRBRAB9ASMARCA2 | |
| SCHEMBL30632492 | 0.87 | MAPT (0.34) | MAPTTACR3THRBRAB9ASMARCA2 | |
| SCHEMBL31293987 | 0.83 | MAPT (0.33) | MAPTTACR3THRB | |
| SCHEMBL31293929 | 0.80 | SMARCA2 (0.30) | SMARCA2SMARCA4PBRM1 | |
| SCHEMBL26888967 | 0.79 | MAPT (0.37) | MAPTTACR3THRBRAB9ASMARCA2 | |
| SCHEMBL30666277 | 0.79 | MAPT (0.32) | MAPTTACR3THRBRAB9A | |
| SCHEMBL26683471 | 0.79 | MAPT (0.32) | MAPTTACR3THRBRAB9A | |
| SCHEMBL30632490 | 0.79 | TACR3 (0.32) | MAPTTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709726-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233717-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-11-14 | — | — | WO | disclosed |