Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 17/20 | 0.37 |
| ▸ | KDM4A | O75164 | 14/20 | 0.37 |
| ▸ | KDM5A | P29375 | 5/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577360 | 0.94 | MEN1 (0.33) | KDM4CKDM5A | |
| SCHEMBL1921576 | 0.87 | MEN1 (0.35) | — | |
| SCHEMBL23703653 | 0.80 | BCHE (0.44) | KDM4CKDM4AKDM5APHF8KDM7A | |
| SCHEMBL23529598 | 0.79 | MEN1 (0.31) | KDM4CKDM5A | |
| SCHEMBL29991123 | 0.79 | ALDH1A1 (0.41) | KDM4CKDM4AKDM5APHF8KDM7A | |
| SCHEMBL24703880 | 0.77 | ALDH1A1 (0.42) | KDM4CKDM4AKDM5APHF8KDM7A | |
| SCHEMBL3059914 | 0.76 | PAOX (0.42) | KDM4CKDM4AKDM5APHF8KDM7A | |
| SCHEMBL1981963 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL27150143 | 0.76 | ALDH1A1 (0.52) | KDM4CKDM4AKDM5APHF8KDM7A | |
| SCHEMBL27152120 | 0.76 | ALDH1A1 (0.52) | KDM4CKDM4AKDM5APHF8KDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261710-A1 | HDAC Inhibitors | ARQULE, INC. (US) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261710-A1 | HDAC Inhibitors | HDAC5, HDAC1, HDAC4 | KDM4C 90/4885KDM4A 93/4885KDM5A 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.