Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21571032 | 0.99 | POLB (0.51) | POLBKMT2AGLAHPGDAPEX1 | |
| Hydrochloric Acid SCHEMBL21571033 | 0.99 | POLB (0.51) | POLBKMT2AGLAHPGDAPEX1 | |
| SCHEMBL26016585 | 0.81 | F12 (0.56) | — | |
| SCHEMBL21579620 | 0.81 | MAPT (0.47) | POLBKMT2AGLAHPGDTSHR | |
| SCHEMBL6185437 | 0.81 | GLA (0.49) | POLBKMT2AGLAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL21571269 | 0.80 | MAPT (0.46) | POLBKMT2AGLAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL30633210 | 0.80 | F12 (0.55) | — | |
| Hydrochloric Acid SCHEMBL30633207 | 0.80 | MAPT (0.46) | POLBKMT2AGLAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL21571265 | 0.80 | MAPT (0.46) | POLBKMT2AGLAHPGDTSHR | |
| SCHEMBL22640183 | 0.77 | HPGD (0.65) | POLBKMT2AHPGDAPEX1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541375-B1 | FACTOR XIIA INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-23 | — | — | EP | disclosed |