Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | HPD | P32754 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638459 | 1.00 | MAOB (0.60) | MAOBHPDTP53CYP3A4APP | |
| SCHEMBL4639016 | 0.89 | MAOB (0.54) | MAOBHPDTP53CYP3A4APP | |
| SCHEMBL4639200 | 0.84 | IDO1 (0.53) | MAOBTP53CYP3A4APPIDO1 | |
| SCHEMBL4638434 | 0.84 | MAOB (0.53) | MAOBTP53CYP3A4APPTSHR | |
| SCHEMBL4639240 | 0.83 | MAOB (0.56) | MAOBHPDTP53CYP3A4APP | |
| SCHEMBL4638735 | 0.83 | MAOB (0.49) | MAOBHPDTP53CYP3A4APP | |
| SCHEMBL31172133 | 0.83 | MAOB (0.59) | MAOBTP53CYP3A4APPKDM4E | |
| SCHEMBL4638517 | 0.83 | MAOB (0.59) | MAOBTP53CYP3A4APPKDM4E | |
| SCHEMBL4638691 | 0.81 | HPD (0.56) | MAOBHPDTP53CYP3A4APP | |
| SCHEMBL22964135 | 0.81 | MAOB (0.57) | MAOBHPDAPPPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-113264874-B | Substituted diaryl urea derivative and preparation method and application thereof | 华东理工大学 | 2024-12-03 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |