Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585845 | 0.83 | HSD17B10 (0.53) | HSD17B10AURKADAPK3JAK2PRKD3 | |
| SCHEMBL29705394 | 0.83 | HSD17B10 (0.53) | HSD17B10AURKADAPK3JAK2PRKD3 | |
| SCHEMBL23416650 | 0.82 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL30635098 | 0.81 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4ADORA2A | |
| SCHEMBL29712818 | 0.81 | GRIA1 (0.53) | HSD17B10GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL24478118 | 0.81 | GRIA1 (0.53) | HSD17B10GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL20703796 | 0.79 | PDE4D (0.41) | HSD17B10AURKADAPK3JAK2PRKD3 | |
| SCHEMBL30635505 | 0.77 | GRIN1 (0.40) | GRIA1GRIA2GRIA3GRIA4ADORA2A | |
| SCHEMBL6073334 | 0.76 | ADORA2A (0.39) | HSD17B10AURKADAPK3JAK2PRKD3 | |
| SCHEMBL29712821 | 0.75 | SCN9A (0.37) | AURKACDK8CDK9GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |