Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171567 | 1.00 | EGFR (0.47) | EGFRPIN1MAOBF10POLB | |
| SCHEMBL30672854 | 0.85 | POLB (0.53) | EGFRPIN1MAOBF10POLB | |
| SCHEMBL4172984 | 0.85 | PIN1 (0.44) | EGFRPIN1MAOBF10POLB | |
| SCHEMBL16706312 | 0.85 | POLB (0.53) | EGFRPIN1MAOBF10POLB | |
| SCHEMBL9945481 | 0.85 | PIN1 (0.47) | EGFRPIN1MAOBF10POLB | |
| SCHEMBL30672829 | 0.83 | PIN1 (0.51) | EGFRPIN1MAOBPOLBMAPT | |
| SCHEMBL16391122 | 0.83 | PIN1 (0.51) | EGFRPIN1MAOBPOLBMAPT | |
| SCHEMBL4173344 | 0.82 | F10 (0.43) | EGFRPIN1MAOBF10POLB | |
| SCHEMBL9945498 | 0.82 | PIN1 (0.49) | EGFRPIN1F10MAPTALDH1A1 | |
| SCHEMBL13068257 | 0.81 | POLB (0.47) | EGFRPIN1MAOBF10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947764-B | Pyrimidamine NUAK inhibitor and preparation method and application thereof | 特科罗生物科技(成都)有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025011444-A1 | PYRIMIDINAMINE NUAK INHIBITOR AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 特科罗生物科技(成都)有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-116947764-A | Pyrimidine amine NUAK inhibitor and preparation method and application thereof | 特科罗生物科技(成都)有限公司 | 2023-10-27 | — | — | CN | disclosed |