SCHEMBL30636600

SCHEMBL30636600

CCOC(OCC)[C@@H](N)c1cccs1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
SLC6A2 P23975 3/20 0.33
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
KEAP1 Q14145 1/20 0.32
MAPT P10636 2/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
SLC7A5 Q01650 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
DPP4 P27487 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409514 0.77 ALOX5 (0.36) ALOX5SLC6A2SLC6A4SLC6A3CES2
SCHEMBL24017067 0.76 ALOX5 (0.42) ALOX5SLC6A2SLC6A4SLC6A3L3MBTL1
SCHEMBL24017068 0.76 ALOX5 (0.42) ALOX5SLC6A2SLC6A4SLC6A3L3MBTL1
SCHEMBL5910731 0.76 ALOX5 (0.39) ALOX5SLC6A2SLC6A4SLC6A3CES2
SCHEMBL5911184 0.74 SLC6A2 (0.38) ALOX5SLC6A2SLC6A4SLC6A3SLC7A5
SCHEMBL10796130 0.74 ALOX5 (0.34) ALOX5SLC6A2SLC6A4SLC6A3CES2
Hydrochloric Acid SCHEMBL30098237 0.74 ALOX5 (0.41) ALOX5SLC6A2SLC6A4SLC6A3L3MBTL1
SCHEMBL10689462 0.73 ALOX5 (0.33) ALOX5SLC6A2SLC6A4SLC6A3CES2
SCHEMBL23695542 0.72 ALOX5 (0.46) ALOX5SLC6A3L3MBTL1CES2CES1
SCHEMBL16169001 0.72 ALOX5 (0.46) ALOX5SLC6A3L3MBTL1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113816865-B Preparation method of chiral alpha-amino acetal compound and derivative thereof 南方科技大学 2023-12-19 CN disclosed