SCHEMBL30636992

SCHEMBL30636992

COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cccc(C(F)(F)F)c3)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 1.00
▸ KAT6A Q92794 20/20 1.00
▸ KAT6B Q8WYB5 9/20 0.79
▸ KAT5 Q92993 9/20 0.79
▸ KAT8 Q9H7Z6 9/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22817448 1.00 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817453 0.92 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817349 0.88 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817406 0.88 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30680819 0.88 KAT7 (0.83) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26969628 0.88 KAT7 (0.83) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30680846 0.88 KAT7 (0.83) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817410 0.86 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30636978 0.86 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817450 0.85 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986890-B9 BENZISOXAZOLE SULFONAMIDE DERIVATIVES PFIZER (US) 2025-04-16 — — EP disclosed
EP-3986890-B1 BENZISOXAZOLE SULFONAMIDE DERIVATIVES PFIZER (US) 2023-11-15 — — EP disclosed
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