SCHEMBL30638633

SCHEMBL30638633

CCOC(=O)c1cc(OC[C@H](C)N)cnc1C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
HSP90AA1 P07900 1/20 0.42
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 4/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.39
DPP4 P27487 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL26660336 0.99 KDM4E (0.44) KDM4EHSP90AA1HSD17B10ALDH1A1NPC1
Hydrochloric Acid SCHEMBL32661050 0.99 KDM4E (0.44) KDM4EHSP90AA1HSD17B10ALDH1A1NPC1
Hydrochloric Acid SCHEMBL26660213 0.99 KDM4E (0.44) KDM4EHSP90AA1HSD17B10ALDH1A1NPC1
SCHEMBL26660304 0.78 ABCB1 (0.40) KDM4EALDH1A1HPGDALOX15
SCHEMBL26660309 0.78 ABCB1 (0.40) KDM4EALDH1A1HPGDALOX15
SCHEMBL30638641 0.78 ABCB1 (0.40) KDM4EALDH1A1HPGDALOX15
SCHEMBL12524199 0.77 KDM4E (0.46) KDM4EHSP90AA1HSD17B10ALDH1A1NPC1
SCHEMBL26660217 0.77 KDM4E (0.37) KDM4EALDH1A1NPC1HPGDALOX15
SCHEMBL26660211 0.77 KDM4E (0.37) KDM4EALDH1A1NPC1HPGDALOX15
SCHEMBL25155336 0.76 HPGD (0.47) KDM4EHSD17B10ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015325-A1 ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-01-15 US disclosed
EP-4522592-A1 ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-03-19 EP disclosed
WO-2023217989-A1 ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015325-A1 ALKOXY HETEROARYL- CARBOXAMIDE OR THIOAMIDE COMPOUNDS CYCS, CBR3, CBR1 KDM4E 3892/4885HSP90AA1 2165/4885HSD17B10 1947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.