Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.62 |
| ▸ | IDO1 | P14902 | 12/20 | 0.58 |
| ▸ | TDO2 | P48775 | 9/20 | 0.53 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614157 | 1.00 | APAF1 (0.62) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639101 | 0.90 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614168 | 0.90 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614173 | 0.86 | APAF1 (0.58) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639109 | 0.86 | APAF1 (0.58) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614146 | 0.84 | APAF1 (0.53) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614091 | 0.83 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614226 | 0.83 | APAF1 (0.49) | APAF1IDO1TDO2IDO2NPC1 | |
| SCHEMBL31382855 | 0.83 | APAF1 (0.49) | APAF1IDO1TDO2IDO2NPC1 | |
| SCHEMBL26614232 | 0.82 | APAF1 (0.57) | APAF1IDO1TDO2IDO2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-119487031-A | Tryptanthrin derivatives and uses thereof | 威森特生物公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |