Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108093 | 1.00 | MAT2A (0.68) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL31145272 | 0.90 | MAT2A (0.76) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL22093264 | 0.90 | MAT2A (0.76) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL22103051 | 0.85 | MAT2A (0.72) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL22093163 | 0.84 | MAT2A (0.68) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL22093097 | 0.84 | MAT2A (0.72) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL31145508 | 0.84 | MAT2A (0.68) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL31145244 | 0.84 | MAT2A (0.68) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL22093368 | 0.84 | MAT2A (0.68) | MAT2AKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL22093256 | 0.84 | MAT2A (0.68) | MAT2AKMT2AMEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196985-A1 | METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-10-12 | — | — | WO | disclosed |