Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 18/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501363 | 0.91 | POLQ (0.47) | POLQDHFR | |
| SCHEMBL24770927 | 0.88 | POLQ (0.45) | POLQ | |
| SCHEMBL30017455 | 0.80 | POLQ (0.75) | POLQ | |
| SCHEMBL24769173 | 0.80 | POLQ (0.75) | POLQ | |
| SCHEMBL27294326 | 0.77 | POLQ (0.58) | POLQDHFR | |
| SCHEMBL24770258 | 0.77 | POLQ (0.45) | POLQDHFR | |
| SCHEMBL31032124 | 0.76 | POLQ (0.80) | POLQ | |
| SCHEMBL24769604 | 0.75 | POLQ (0.44) | POLQDHFR | |
| SCHEMBL29261657 | 0.73 | POLQ (0.46) | POLQDHFR | |
| SCHEMBL24770262 | 0.73 | POLQ (0.45) | POLQDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083271-A | Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors | 伊迪亚生物科学有限公司 | 2023-11-17 | — | — | CN | disclosed |