Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 12/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 7/20 | 0.45 |
| ▸ | FLT1 | P17948 | 6/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.45 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.44 |
| ▸ | TEC | P42680 | 1/20 | 0.44 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.44 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30264654 | 0.87 | EGFR (0.53) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL30640332 | 0.85 | EGFR (0.59) | EGFRERBB2EPHB4KDRKCNH2 | |
| SCHEMBL30640277 | 0.83 | EGFR (0.70) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL30640294 | 0.82 | EGFR (0.66) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL20865233 | 0.74 | EGFR (1.00) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL31004057 | 0.74 | EGFR (1.00) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL30264488 | 0.74 | EGFR (0.58) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL30126264 | 0.73 | EGFR (0.46) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL30264452 | 0.73 | EGFR (0.54) | EGFRERBB2EPHA2FLT1EPHB4 | |
| SCHEMBL30264625 | 0.73 | EGFR (0.53) | EGFRERBB2EPHA2FLT1EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079830-B | Inhibitor containing fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |