Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267082 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL3274182 | 0.84 | ALDH1A1 (0.59) | CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL6041439 | 0.82 | TYMS (0.41) | CYP1A2CYP2A6ALDH1A1KDM4ELMNA | |
| SCHEMBL32664327 | 0.81 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL3267833 | 0.78 | CYP3A4 (0.43) | CYP1A2CYP2A6ALDH1A1LMNAHPGD | |
| SCHEMBL28795619 | 0.78 | POLB (0.55) | CYP1A2CYP2A6ALDH1A1HSD17B10LMNA | |
| SCHEMBL3268719 | 0.78 | TYMS (0.39) | CYP1A2CYP2A6ALDH1A1TSHRMAPT | |
| SCHEMBL30694959 | 0.77 | CYP1A2 (0.65) | CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL599276 | 0.77 | CYP1A2 (0.65) | CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E | |
| SCHEMBL30518173 | 0.76 | CYP1A2 (0.58) | CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039233-A | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118994028-A | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113166075-B | Pyridazinone herbicides and pyridazinone intermediates for preparing the same | FMC公司 | 2024-10-25 | — | — | CN | disclosed |
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |