Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26621931 | 1.00 | MAPT (0.52) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL20205620 | 0.90 | MAPT (0.53) | MAPTALDH1A1TDP1KMT2AKDM4E | |
| SCHEMBL17489598 | 0.87 | MAPT (0.54) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL3823602 | 0.84 | MAPT (0.58) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL1806126 | 0.84 | MAPT (0.55) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL1809661 | 0.84 | MAPT (0.55) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL31048348 | 0.84 | MAPT (0.58) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL11971460 | 0.84 | MAPT (0.55) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL31154857 | 0.84 | MAPT (0.58) | MAPTMAPK1ALDH1A1TDP1KMT2A | |
| SCHEMBL13019970 | 0.84 | MAPT (0.58) | MAPTMAPK1ALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023214325-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS | NOVARTIS AG (CH) | 2023-11-09 | — | — | WO | disclosed |