SCHEMBL20205620

SCHEMBL20205620

COc1ccc2c(c1)CC/C2=N\N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
RAB9A P51151 5/20 0.53
NPC1 O15118 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51
CYP2C19 P33261 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
NFKB1 P19838 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 3/20 0.49
HTT P42858 1/20 0.49
MPO P05164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30640490 0.90 MAPT (0.52) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL26621931 0.90 MAPT (0.52) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL20205914 0.86 MAPT (0.51) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL355825 0.83 HTT (0.57) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL16082212 0.83 HTT (0.57) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL355824 0.83 HTT (0.57) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL17108416 0.81 MPO (0.59) MAPTRAB9ASMN1; SMN2CYP1A2CYP2D6
SCHEMBL13644349 0.80 MAPT (0.54) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL30460763 0.79 MAPT (0.47) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL30460762 0.78 METAP1 (0.53) MAPTRAB9ANPC1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-01-18 US disclosed
EP-3544973-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL CO (JP) 2021-07-28 EP disclosed
WO-2018097318-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents CYC1, MT-CO1, CTRL MAPT 3767/4885RAB9A 3323/4885NPC1 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.