Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 11/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092135 | 1.00 | GRM2 (0.36) | GRM2GPR139NPC1POLBGAA | |
| Trifluoroacetic Acid SCHEMBL22092166 | 0.94 | GPR139 (0.34) | GRM2GPR139NPC1POLBGAA | |
| SCHEMBL22098839 | 0.86 | NPC1 (0.35) | GRM2GPR139NPC1POLBGAA | |
| Hydrochloric Acid SCHEMBL22206329 | 0.85 | NPC1 (0.34) | GRM2GPR139NPC1POLBGAA | |
| SCHEMBL30641014 | 0.84 | GPR139 (0.37) | GPR139PIK3CA | |
| SCHEMBL22092076 | 0.84 | GPR139 (0.37) | GPR139PIK3CA | |
| SCHEMBL22098775 | 0.83 | MCHR1 (0.37) | GPR139PIK3CDPIK3CAPIK3CBPI4KA | |
| Trifluoroacetic Acid SCHEMBL22092139 | 0.80 | MCHR1 (0.35) | GPR139PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL22098776 | 0.79 | FLT3 (0.41) | GPR139PIK3CGTDO2 | |
| SCHEMBL22092061 | 0.78 | PRMT5 (0.39) | GPR139PIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820769-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820769-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | VAPB, HDLBP, VAPA | GRM2 4441/4885GPR139 4033/4885NPC1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.