Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BACH1 | O14867 | 1/20 | 0.32 |
| ▸ | MAFK | O60675 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL3061402 | 0.97 | MIF (0.41) | MIFNAAAALDH1A1TSHRKEAP1 | |
| Alcohol SCHEMBL3066588 | 0.97 | MIF (0.41) | MIFNAAAALDH1A1TSHRKEAP1 | |
| Alcohol SCHEMBL8854151 | 0.91 | NAAA (0.52) | MIFNAAAALDH1A1TSHRLMNA | |
| Propanol SCHEMBL13506048 | 0.87 | NAAA (0.43) | MIFNAAAALDH1A1TSHRLMNA | |
| Ethylene Glycol SCHEMBL7643803 | 0.86 | MIF (0.44) | MIF | |
| Propane SCHEMBL28095764 | 0.86 | NAAA (0.44) | MIFNAAAALDH1A1TSHRKEAP1 | |
| Methyl Alcohol SCHEMBL7039090 | 0.86 | MIF (0.39) | MIFNAAAALDH1A1TSHRKEAP1 | |
| SCHEMBL20391 | 0.85 | MIF (0.33) | MIFNAAAALDH1A1KEAP1NFE2L2 | |
| Ethylene Glycol SCHEMBL2978523 | 0.83 | MIF (0.48) | MIFNAAAGSK3B | |
| Ethylene Glycol SCHEMBL29254250 | 0.83 | MIF (0.48) | MIFNAAAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426096-B2 | Capsule toner and method of manufacturing capsule toner | SHARP KABUSHIKI KAISHA (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20100266947-A1 | CAPSULE TONER AND METHOD OF MANUFACTURING CAPSULE TONER | SHARP KABUSHIKI KAISHA (JP) | 2010-10-21 | — | — | US | disclosed |