Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSC | P53634 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31276654 | 1.00 | AKR1C3 (0.47) | AKR1C3MEN1KMT2ASOS1CYP1A1 | |
| SCHEMBL30644263 | 0.91 | AKR1C3 (0.41) | AKR1C3MEN1KMT2ASOS1CYP1A1 | |
| SCHEMBL16427192 | 0.85 | AKR1C3 (0.49) | AKR1C3MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL29964545 | 0.85 | AKR1C3 (0.47) | AKR1C3SOS1HRH3CTSKCTSC | |
| SCHEMBL15551984 | 0.85 | SOS1 (0.41) | MEN1KMT2ASOS1HSD17B10HRH3 | |
| SCHEMBL29964729 | 0.85 | AKR1C3 (0.47) | AKR1C3SOS1HRH3CTSKCTSC | |
| SCHEMBL29964783 | 0.85 | AKR1C3 (0.47) | AKR1C3SOS1HRH3CTSKCTSC | |
| SCHEMBL16440196 | 0.85 | AKR1C3 (0.47) | AKR1C3MEN1KMT2ASOS1HSD17B10 | |
| SCHEMBL15551986 | 0.85 | SOS1 (0.41) | MEN1KMT2ASOS1HSD17B10HRH3 | |
| SCHEMBL16292255 | 0.82 | AKR1C3 (0.49) | AKR1C3MEN1KMT2ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |