Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31276654 | 0.91 | AKR1C3 (0.47) | AKR1C3L3MBTL3MEN1KMT2AHRH3 | |
| SCHEMBL30644253 | 0.91 | AKR1C3 (0.47) | AKR1C3L3MBTL3MEN1KMT2AHRH3 | |
| SCHEMBL29965093 | 0.80 | HRH3 (0.52) | L3MBTL3L3MBTL1HRH3ADRA2AADRA2B | |
| SCHEMBL16292255 | 0.80 | AKR1C3 (0.49) | AKR1C3L3MBTL3L3MBTL1MEN1KMT2A | |
| SCHEMBL16427192 | 0.77 | AKR1C3 (0.49) | AKR1C3L3MBTL3L3MBTL1MEN1KMT2A | |
| SCHEMBL29964545 | 0.77 | AKR1C3 (0.47) | AKR1C3L3MBTL3L3MBTL1HRH3SOS1 | |
| SCHEMBL15551984 | 0.77 | SOS1 (0.41) | L3MBTL1MEN1KMT2AHRH3SOS1 | |
| SCHEMBL29964729 | 0.77 | AKR1C3 (0.47) | AKR1C3L3MBTL3L3MBTL1HRH3SOS1 | |
| SCHEMBL16440196 | 0.77 | AKR1C3 (0.47) | AKR1C3L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL29964783 | 0.77 | AKR1C3 (0.47) | AKR1C3L3MBTL3L3MBTL1HRH3SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |