Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743026 | 1.00 | SOS1 (0.42) | SOS1MAPTRAF1BRAFMTOR | |
| Trifluoroacetic Acid SCHEMBL22188697 | 0.97 | SOS1 (0.42) | SOS1MAPTRAF1BRAFMTOR | |
| SCHEMBL20743019 | 0.88 | SOS1 (0.45) | SOS1MAPTRAF1MTORTEK | |
| SCHEMBL20743025 | 0.87 | MTOR (0.49) | MAPTMTORTP53KMT2AMEN1 | |
| SCHEMBL30645019 | 0.86 | NPC1 (0.47) | SOS1RAF1BRAFMTORITGA5 | |
| SCHEMBL20743761 | 0.86 | NPC1 (0.47) | SOS1RAF1BRAFMTORITGA5 | |
| SCHEMBL20762081 | 0.81 | SOS1 (0.41) | SOS1ITGA5ITGB6ITGB8KMT2A | |
| SCHEMBL30645122 | 0.80 | MAPT (0.42) | SOS1MAPTRAF1BRAFMTOR | |
| SCHEMBL20743101 | 0.79 | SOS1 (0.46) | SOS1ITGA5ITGB6ITGB8KMT2A | |
| SCHEMBL30645115 | 0.79 | SOS1 (0.46) | SOS1ITGA5ITGB6ITGB8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | claimed |
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |