Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645017 | 0.80 | SOS1 (0.42) | MAPTMTORRAF1BRAFTEK | |
| SCHEMBL20743026 | 0.80 | SOS1 (0.42) | MAPTMTORRAF1BRAFTEK | |
| Trifluoroacetic Acid SCHEMBL22188697 | 0.77 | SOS1 (0.42) | MAPTMTORRAF1BRAFTEK | |
| SCHEMBL19283585 | 0.69 | MTOR (0.47) | MAPTMTORRAF1BRAFTEK | |
| SCHEMBL15111478 | 0.69 | COASY (0.48) | AURKAEPHX1SOS1 | |
| SCHEMBL19284055 | 0.67 | ITGA5 (0.50) | MTORRAF1BRAFKDM4ESOS1 | |
| SCHEMBL19283712 | 0.67 | MTOR (0.50) | MTORRAF1BRAFITGA5ITGB6 | |
| SCHEMBL19283637 | 0.67 | ITGA5 (0.47) | MAPTMTORRAF1BRAFTEK | |
| SCHEMBL20743019 | 0.67 | SOS1 (0.45) | MAPTMTORRAF1TEKKDR | |
| SCHEMBL20743022 | 0.66 | KLRK1 (0.49) | MTORKMT2AITGA5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |