Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22188672 | 1.00 | ITGA5 (0.44) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL23679179 | 0.86 | SLC6A2 (0.47) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL20792208 | 0.86 | PNMT (0.47) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| Hydrochloric Acid SCHEMBL22321392 | 0.85 | PNMT (0.46) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| Hydrochloric Acid SCHEMBL30411743 | 0.85 | PNMT (0.46) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL20743024 | 0.83 | ITGA5 (0.45) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL20743289 | 0.83 | ITGA5 (0.45) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL19283808 | 0.83 | ITGA5 (0.47) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL20764702 | 0.82 | ITGA5 (0.46) | ITGA5ITGB6ITGB8MTORNTRK1 | |
| SCHEMBL20764688 | 0.82 | ITGA5 (0.46) | ITGA5ITGB6ITGB8MTORNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |