Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365306 | 1.00 | FFAR4 (0.54) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL12993003 | 0.86 | SIRT2 (0.49) | FFAR4KDM4EMEN1KMT2AHDAC8 | |
| SCHEMBL11244569 | 0.86 | FFAR1 (0.76) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL28191746 | 0.85 | FFAR4 (0.52) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL6173881 | 0.85 | FFAR4 (0.52) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL901880 | 0.85 | FFAR4 (0.55) | FFAR4KDM4EKMT2AFFAR1TAAR1 | |
| SCHEMBL14026853 | 0.85 | MAOB (0.47) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL10868609 | 0.85 | FFAR4 (0.45) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL10868603 | 0.85 | FFAR4 (0.45) | FFAR4KDM4EMEN1KMT2AFFAR1 | |
| SCHEMBL12646504 | 0.85 | MAOB (0.57) | FFAR4FFAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |