Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GNA15 | P30679 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249779 | 0.90 | FFAR1 (0.71) | FFAR1FFAR4TDP1GNA15PTGER3 | |
| SCHEMBL11242235 | 0.88 | FFAR1 (0.80) | FFAR1FFAR4TDP1GNA15PTGER3 | |
| SCHEMBL11233308 | 0.88 | FFAR1 (0.65) | FFAR1FFAR4TDP1KDM4EMEN1 | |
| SCHEMBL13840567 | 0.87 | FFAR1 (0.59) | FFAR1FFAR4TDP1GNA15PTGER3 | |
| SCHEMBL30645136 | 0.86 | FFAR4 (0.54) | FFAR1FFAR4TDP1KDM4EMEN1 | |
| SCHEMBL365306 | 0.86 | FFAR4 (0.54) | FFAR1FFAR4TDP1KDM4EMEN1 | |
| SCHEMBL11244562 | 0.81 | RXFP1 (0.54) | FFAR1FFAR4TDP1KDM4EMEN1 | |
| SCHEMBL12059419 | 0.81 | MAPT (0.61) | MEN1KMT2A | |
| SCHEMBL12646504 | 0.80 | MAOB (0.57) | FFAR1FFAR4 | |
| SCHEMBL11240957 | 0.80 | FFAR1 (0.67) | FFAR1FFAR4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |