Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.56 |
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 10/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31505408 | 1.00 | ESR2 (0.56) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL31505338 | 1.00 | ESR2 (0.56) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL24528817 | 1.00 | ESR2 (0.56) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL31505332 | 1.00 | ESR2 (0.56) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL21470624 | 0.90 | ESR2 (0.56) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL21470623 | 0.90 | ESR2 (0.56) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL18617672 | 0.87 | LMNA (0.45) | ESR2NR1H2SMN1; SMN2GHSR | |
| SCHEMBL4183874 | 0.86 | NR1H2 (0.60) | ESR2NR1H2SMN1; SMN2GHSRDRD1 | |
| SCHEMBL12280043 | 0.86 | NR1H2 (0.43) | ESR2ESR1NR1H2SMN1; SMN2GHSR | |
| SCHEMBL29676621 | 0.86 | NR1H2 (0.43) | ESR2ESR1NR1H2SMN1; SMN2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116897150-A | Novel bifunctional molecules for protein-targeted degradation | 安菲斯塔治疗有限公司 | 2023-10-17 | — | — | CN | disclosed |