Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30075081 | 0.89 | ALOX5 (0.44) | ALOX5MAOBAPP | |
| SCHEMBL16406480 | 0.89 | ALOX5 (0.44) | ALOX5MAOBAPP | |
| SCHEMBL16406504 | 0.89 | ALOX5 (0.44) | ALOX5MAOBAPP | |
| SCHEMBL16406491 | 0.86 | ALOX5 (0.42) | ALOX5MAOBAPPNR1H4BACE1 | |
| SCHEMBL16406481 | 0.81 | ALOX5 (0.41) | ALOX5MAOB | |
| SCHEMBL16406484 | 0.80 | ALOX5 (0.44) | ALOX5MAOB | |
| SCHEMBL16406492 | 0.80 | APP (0.44) | ALOX5MAOBAPPNR1H4BACE1 | |
| SCHEMBL16406485 | 0.78 | APP (0.45) | ALOX5MAOBAPPNR1H4BACE1 | |
| SCHEMBL16406483 | 0.78 | ALOX5 (0.41) | ALOX5MAOB | |
| SCHEMBL908611 | 0.77 | ST6GAL1 (0.41) | ALOX5APPNR1H4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116687920-A | Application of marine bisindole compound combined with cytarabine (Ara-C) in preparation of drugs for treating Acute Myeloid Leukemia (AML) | 上海海洋大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116687920-A | Application of marine bisindole compound combined with cytarabine (Ara-C) in preparation of drugs for treating Acute Myeloid Leukemia (AML) | 上海海洋大学 | 2023-09-05 | — | — | CN | disclosed |