Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771229 | 1.00 | RXRA (0.41) | RXRARXRBRXRGESR1MGLL | |
| SCHEMBL18720901 | 0.92 | RXRA (0.41) | RXRARXRBRXRGESR1MGLL | |
| SCHEMBL793354 | 0.91 | ESR1 (0.46) | RXRARXRBRXRGESR1S1PR1 | |
| SCHEMBL793353 | 0.91 | ESR1 (0.46) | RXRARXRBRXRGESR1S1PR1 | |
| SCHEMBL793355 | 0.91 | ESR1 (0.46) | RXRARXRBRXRGESR1S1PR1 | |
| SCHEMBL18720914 | 0.90 | RXRA (0.44) | RXRARXRBRXRGESR1CYP4F2 | |
| SCHEMBL18720908 | 0.88 | RXRA (0.45) | RXRARXRBRXRGESR1ALDH1A1 | |
| SCHEMBL22656814 | 0.86 | RXRA (0.47) | RXRARXRBRXRGESR1ALDH1A1 | |
| SCHEMBL22656810 | 0.86 | RXRA (0.47) | RXRARXRBRXRGESR1ALDH1A1 | |
| SCHEMBL29536400 | 0.86 | RXRA (0.47) | RXRARXRBRXRGESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |