Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211526 | 1.00 | GFER (0.61) | GFERATMKDM4EGAAALDH1A1 | |
| SCHEMBL10211528 | 0.84 | GFER (0.57) | GFERATMALDH1A1MEN1KMT2A | |
| SCHEMBL1472855 | 0.83 | GFER (0.64) | GFERATMALDH1A1MEN1KMT2A | |
| SCHEMBL2283356 | 0.81 | GFER (0.62) | GFERATMKDM4EALDH1A1MEN1 | |
| SCHEMBL24160846 | 0.81 | KDM4E (0.51) | GFERKDM4EGAAALDH1A1HRH3 | |
| SCHEMBL14697458 | 0.77 | KDM4E (0.51) | GFERATMKDM4EGAAALDH1A1 | |
| SCHEMBL9840017 | 0.77 | KDM4E (0.51) | GFERATMKDM4EGAAALDH1A1 | |
| SCHEMBL13990823 | 0.77 | KDM4E (0.51) | GFERKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL9840022 | 0.77 | KDM4E (0.51) | GFERATMKDM4EGAAALDH1A1 | |
| SCHEMBL7329753 | 0.77 | KDM4E (0.55) | KDM4EGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202583-A1 | FXR REGULATOR AND USE THEREOF | 北京大学 | 2023-10-26 | — | — | WO | disclosed |