Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811140 | 0.98 | KDM4E (0.53) | KDM4EGAAHRH3ACHEALDH1A1 | |
| SCHEMBL11186313 | 0.90 | ALDH1A1 (0.50) | KDM4EGAAALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4143256 | 0.83 | HTT (0.61) | HRH3ALDH1A1CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL11523316 | 0.82 | ALDH1A1 (0.41) | KDM4EGAAALDH1A1NPC1NPSR1 | |
| SCHEMBL4144775 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1NPC1SMN1; SMN2NPSR1 | |
| SCHEMBL24160846 | 0.81 | KDM4E (0.51) | KDM4EGAAHRH3ACHEALDH1A1 | |
| SCHEMBL13990823 | 0.81 | KDM4E (0.51) | KDM4EGAAHRH3ACHEALDH1A1 | |
| SCHEMBL9840022 | 0.81 | KDM4E (0.51) | KDM4EGAAHRH3ACHEALDH1A1 | |
| SCHEMBL9840017 | 0.81 | KDM4E (0.51) | KDM4EGAAHRH3ACHEALDH1A1 | |
| SCHEMBL14375213 | 0.79 | ACHE (0.49) | HRH3ACHEALDH1A1NPSR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | disclosed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | disclosed |
| US-5017586-A | 5-dialkylaminomethyl-2-furanomethanol derivatives having anti-hypertensive properties | GEROT-PHARMAZEUTIKA GESELLSCHAFT M.B.H. (AT) | 1991-05-21 | — | — | US | disclosed |
| EP-0342182-A1 | Derivatives of 5-aminomethyl-2-furan methanol, their preparation and use | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1989-11-15 | — | — | EP | disclosed |
| US-4837316-A | ANTIULCER AGENTS | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0214823-A2 | Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1987-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | GLS, SQOR, GCDH | KDM4E 3516/4885GAA 617/4885HRH3 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.