Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20584210 | 0.84 | PPARG (0.44) | KMT2AGAAPPARGL3MBTL1NPC1 | |
| SCHEMBL28833896 | 0.79 | PPARG (0.47) | KMT2AGAAPPARGHTT | |
| SCHEMBL30647990 | 0.79 | MGMT (0.52) | L3MBTL1 | |
| SCHEMBL30647979 | 0.76 | POLB (0.50) | KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL23481535 | 0.76 | PPARG (0.42) | KMT2AGAAPPARGL3MBTL1SMN1; SMN2 | |
| SCHEMBL23415264 | 0.74 | P2RX3 (0.46) | PPARG | |
| SCHEMBL1101906 | 0.73 | NPSR1 (0.50) | KMT2AGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL31521323 | 0.72 | HRH4 (0.34) | KMT2AGAAPPARG | |
| SCHEMBL1053863 | 0.71 | PPARG (0.49) | KMT2APPARGL3MBTL1HTT | |
| SCHEMBL23481522 | 0.71 | PPARG (0.36) | KMT2APPARGL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522594-A1 | PTPN2 INHIBITORS | Ness Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220572-A1 | PTPN2 INHIBITORS | NESS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |