SCHEMBL30648440

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	15/20	0.65

▸	CALCR	P30988	15/20	0.65

▸	MAPK8	P45983	1/20	0.56

▸	MAPK9	P45984	1/20	0.56

▸	MAPK10	P53779	1/20	0.56

▸	NPY2R	P49146	3/20	0.55

▸	NPY4R	P50391	3/20	0.55

▸	NPY5R	Q15761	3/20	0.55

▸	NPY1R	P25929	2/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30726569	0.92	RAMP3 (0.63)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL29949632	0.91	MAPK8 (0.59)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL31031543	0.90	RAMP3 (0.66)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL31683337	0.90	NPY2R (0.61)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL29827221	0.89	NPY2R (0.59)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL30712958	0.89	NPY2R (0.60)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30429234	0.88	EP300 (0.62)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL29949435	0.88	NPY2R (0.58)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL31043443	0.88	NPY2R (0.59)	RAMP3CALCRMAPK8MAPK9MAPK10
SCHEMBL31031585	0.88	RAMP3 (0.63)	RAMP3CALCRNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116948034-B	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2024-06-25	—	—	CN	disclosed
CN-116948034-A	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2023-10-27	—	—	CN	disclosed