Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.54 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.51 |
| ▸ | GRPR | P30550 | 1/20 | 0.51 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31672213 | 0.87 | CALCR (0.70) | CALCRF2CRHR1CRHR2 | |
| SCHEMBL29706318 | 0.87 | CALCR (0.54) | CALCRF2CXCL8CRHR1CRHR2 | |
| SCHEMBL30547344 | 0.87 | EPHA2 (0.55) | CALCRF2NMUR2 | |
| SCHEMBL31119149 | 0.87 | F2 (0.52) | CALCRF2CXCL8NMUR2 | |
| SCHEMBL30437384 | 0.85 | APLNR (0.60) | CALCRCRHR1CRHR2 | |
| SCHEMBL30431687 | 0.84 | F2 (0.64) | CALCRF2CXCL8CRHR1CRHR2 | |
| SCHEMBL30208250 | 0.84 | EPHA2 (0.56) | F2NMUR2 | |
| SCHEMBL31583875 | 0.84 | NMUR2 (0.54) | F2NMUR2 | |
| SCHEMBL30495679 | 0.83 | CALCR (0.55) | CALCRF2CRHR1CRHR2NMBR | |
| SCHEMBL29802631 | 0.83 | SLC6A2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116948034-B | Active type heterophagy antibody blocker Block-5S and preparation method thereof | 南京珀尔泰生物技术有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-116948034-A | Active type heterophagy antibody blocker Block-5S and preparation method thereof | 南京珀尔泰生物技术有限公司 | 2023-10-27 | — | — | CN | disclosed |