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SCHEMBL30648443

SCHEMBL30648443

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(C)C)C(C)C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.54
▸ NPY4R P50391 8/20 0.54
▸ NPY5R Q15761 8/20 0.54
▸ NPY1R P25929 6/20 0.54
▸ CALCR P30988 4/20 0.51
▸ TFPI P10646 2/20 0.50
▸ CXCR4 P61073 1/20 0.50
▸ APLNR P35414 1/20 0.50
▸ OPRD1 P41143 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29855903 0.95 NPY2R (0.53) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29479863 0.93 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30567707 0.92 NPY2R (0.58) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31688335 0.90 NPY2R (0.52) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30648444 0.89 NPY2R (0.51) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29479866 0.89 NPY2R (0.51) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30432870 0.88 NPY2R (0.59) NPY2RNPY4RNPY5RNPY1RCALCR
Human C-Peptide SCHEMBL29353643 0.87 NPY2R (0.50) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30176504 0.87 NPY2R (0.55) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30906472 0.86 EP300 (0.54) NPY2RNPY4RNPY5RNPY1RCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948034-B Active type heterophagy antibody blocker Block-5S and preparation method thereof 南京珀尔泰生物技术有限公司 2024-06-25 — — CN disclosed
CN-116948034-A Active type heterophagy antibody blocker Block-5S and preparation method thereof 南京珀尔泰生物技术有限公司 2023-10-27 — — CN disclosed
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