SCHEMBL30648454

CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)O)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	3/20	0.69

▸	GCGR	P47871	1/20	0.69

▸	GIPR	P48546	1/20	0.69

▸	IL23R	Q5VWK5	10/20	0.66

▸	ECE1	P42892	1/20	0.65

▸	MUS81	Q96NY9	1/20	0.65

▸	NR3C1	P04150	4/20	0.65

▸	CCKBR	P32239	1/20	0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29479897	0.96	IL23R (0.65)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL31000880	0.94	IL23R (0.68)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL31683350	0.92	CCKBR (0.65)	GLP1RGCGRGIPRIL23RCCKBR
SCHEMBL30906442	0.91	GLP1R (0.66)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL30906466	0.91	GLP1R (0.66)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL30906474	0.91	GLP1R (0.67)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL30906573	0.90	IL23R (0.68)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL30906562	0.90	IL23R (0.68)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL29383678	0.90	GLP1R (0.77)	GLP1RGCGRGIPRIL23RECE1
SCHEMBL30299221	0.89	GLP1R (0.73)	GLP1RGCGRGIPRECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116948034-B	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2024-06-25	—	—	CN	disclosed
CN-116948034-A	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2023-10-27	—	—	CN	disclosed