SCHEMBL30648595

SCHEMBL30648595

C=C[C@@H](CSc1ccc(Cl)cc1)[C@@H](O)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
MITF O75030 1/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
ALOX15 P16050 1/20 0.38
POLB P06746 2/20 0.36
RAB9A P51151 4/20 0.34
NPC1 O15118 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CTSK P43235 1/20 0.33
BCL2L1 Q07817 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648591 0.86 NPC1 (0.45) HPGDKMT2AMEN1TSHRALDH1A1
SCHEMBL30648575 0.69 MMP2 (0.40) KMT2AMEN1CYP1A2CYP2C19CYP2D6
SCHEMBL30648573 0.68 PPARG (0.39) HPGDKMT2AMEN1ALDH1A1MAPT
SCHEMBL2951287 0.63 NPC1 (0.53) HPGDKMT2ATSHRALDH1A1MAPT
SCHEMBL1496584 0.63 HPGD (0.47) HPGDKMT2AMEN1TSHRALDH1A1
SCHEMBL10940903 0.62 TP53 (0.32) MAPTSMN1; SMN2KDM4E
SCHEMBL10940905 0.62 TP53 (0.32) MAPTSMN1; SMN2KDM4E
SCHEMBL1496583 0.62 TEAD1 (0.42) HPGDKMT2AMEN1ALDH1A1MAPT
SCHEMBL1496675 0.62 CYP2D6 (0.40) HPGDKMT2AMEN1ALDH1A1MAPT
SCHEMBL28438873 0.62 DHODH (0.54) HPGDALDH1A1MAPTALOX15POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304081-A Method for synthesizing homoallylic alcohol compound by synergistic catalysis of visible light and titanium 河南师范大学 2023-12-29 CN disclosed