Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12244114 | 0.80 | KDM4E (0.48) | ADRA1AKDM4EDRD3NR2E1 | |
| SCHEMBL19139017 | 0.77 | KDM4E (0.46) | ADRA1AKDM4EDRD3NR2E1 | |
| SCHEMBL11883126 | 0.74 | DRD3 (0.50) | ADRA1AKDM4EDRD3 | |
| SCHEMBL7407267 | 0.69 | NR2E1 (0.58) | ADRA1ANR2E1CHRNA7 | |
| SCHEMBL9688892 | 0.68 | KDM4E (0.66) | ADRA1AKDM4EDRD3CHRNA7 | |
| SCHEMBL20695909 | 0.68 | ADRA1A (0.70) | ADRA1AKDM4EDRD3CHRNA7 | |
| SCHEMBL12564952 | 0.68 | KDM4E (0.50) | KDM4ENR2E1CHRNA7 | |
| SCHEMBL25424716 | 0.68 | NR2E1 (0.54) | ADRA1AKDM4EDRD3NR2E1CHRNA7 | |
| SCHEMBL25424582 | 0.68 | NR2E1 (0.54) | ADRA1AKDM4EDRD3NR2E1CHRNA7 | |
| SCHEMBL25423066 | 0.68 | NR2E1 (0.54) | ADRA1AKDM4EDRD3NR2E1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |