Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16824859 | 1.00 | RXFP1 (0.48) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL16824896 | 0.92 | RXFP1 (0.52) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL16824972 | 0.88 | RXFP1 (0.58) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL15206053 | 0.87 | MEN1 (0.62) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL30656466 | 0.87 | MEN1 (0.62) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL20874058 | 0.87 | RXFP1 (0.49) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL15207007 | 0.85 | LMNA (0.54) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL28094395 | 0.84 | RXFP1 (0.46) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL16824895 | 0.82 | MAPT (0.67) | RXFP1MEN1KMT2AMAPTAHR | |
| SCHEMBL16824904 | 0.80 | RXFP1 (0.48) | RXFP1MEN1KMT2AMAPTAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217201-A2 | NOVEL PYRIMIDO-HETEROCYCLIC NOVEL COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATION THEREOF | 杭州德睿智药科技有限公司 | 2023-11-16 | — | — | WO | disclosed |