Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26632969 | 1.00 | ADORA2A (0.63) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL26632975 | 0.87 | ADORA2A (0.70) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL30656072 | 0.87 | ADORA2A (0.70) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL26632976 | 0.86 | ADORA2A (0.63) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL31215450 | 0.83 | ADORA2A (0.71) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL26632970 | 0.83 | ADORA2A (0.71) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL26632965 | 0.83 | ADORA2A (0.70) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL31215451 | 0.83 | ADORA2A (0.70) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL26632986 | 0.83 | ADORA2A (0.70) | ADORA2AKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL31215458 | 0.83 | ADORA2A (0.69) | ADORA2AKDM4EHPGDALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-B1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIV GENEVE (CH) | 2025-08-20 | — | — | EP | claimed |
| CN-119136802-A | Adenosine 2A receptor modulators for the treatment of cancer | 瑞士日内瓦大学 | 2024-12-13 | — | — | CN | claimed |
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | claimed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | claimed |
| EP-4447962-B1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIV GENEVE (CH) | 2025-08-20 | — | — | EP | disclosed |
| US-20250115592-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2025-04-10 | — | — | US | disclosed |
| CN-119136802-A | Adenosine 2A receptor modulators for the treatment of cancer | 瑞士日内瓦大学 | 2024-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115592-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | ADORA2A, ADORA2B, ADORA1 | ADORA2A 1/4885KDM4E 2545/4885HPGD 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.