Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | KDM1A | O60341 | 8/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26828960 | 1.00 | SIGMAR1 (0.53) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL26665001 | 1.00 | SIGMAR1 (0.53) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL30656611 | 1.00 | SIGMAR1 (0.53) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL26665066 | 1.00 | SIGMAR1 (0.53) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL26829071 | 0.87 | SIGMAR1 (0.54) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL26665027 | 0.87 | SIGMAR1 (0.54) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL26664998 | 0.83 | SIGMAR1 (0.47) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL26665031 | 0.83 | SIGMAR1 (0.47) | SIGMAR1KDM1AMAOBMAOATMEM97 | |
| SCHEMBL18100594 | 0.81 | SIGMAR1 (0.68) | SIGMAR1TMEM97KDM2B | |
| SCHEMBL30656546 | 0.79 | SIGMAR1 (0.45) | SIGMAR1KDM1AMAOBMAOATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4525879-A2 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | Board of Regents, The University of Texas System (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225563-A2 | SELECTIVE SIGMA-2 RECEPTOR LIGANDS AS MODULATORS OF TMEM97 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-23 | — | — | WO | disclosed |