SCHEMBL30656643

SCHEMBL30656643

O=C(Nc1nnc(-c2ccccc2)o1)c1cccc(Br)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.72
LMNA P02545 4/20 0.72
HTT P42858 3/20 0.72
L3MBTL1 Q9Y468 3/20 0.72
ADCY1 Q08828 7/20 0.69
ADCY8 P40145 2/20 0.69
ALDH1A1 P00352 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.63
ALOX15 P16050 1/20 0.63
ALOX12 P18054 1/20 0.63
CXCR5 P32302 1/20 0.63
APLNR P35414 1/20 0.63
OPRK1 P41145 1/20 0.63
CCR6 P51684 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
NPC1 O15118 1/20 0.61
HPGD P15428 1/20 0.61
TSHR P16473 1/20 0.61
RAB9A P51151 1/20 0.61
GFER P55789 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26665252 1.00 KDM4E (0.72) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL17717128 0.92 KDM4E (0.69) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL17717116 0.89 ADCY1 (0.80) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL17717011 0.87 KDM4E (0.76) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL17717017 0.86 KDM4E (0.65) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL28823005 0.86 KDM4E (0.83) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL30656646 0.85 KDM4E (0.60) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL26665215 0.85 KDM4E (0.60) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL26665242 0.85 ADCY1 (0.76) KDM4ELMNAHTTL3MBTL1ADCY1
SCHEMBL30656657 0.85 ADCY1 (0.76) KDM4ELMNAHTTL3MBTL1ADCY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023224371-A1 NOVEL OXADIAZOLE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY DISEASES COMPRISING SAME (주)셀로스바이오텍 2023-11-23 WO claimed
WO-2023224371-A1 NOVEL OXADIAZOLE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY DISEASES COMPRISING SAME (주)셀로스바이오텍 2023-11-23 WO disclosed