Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.74 |
| ▸ | CCR6 | P51684 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.74 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.74 |
| ▸ | APLNR | P35414 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | ADCY1 | Q08828 | 8/20 | 0.64 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26665265 | 1.00 | KDM4E (0.74) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL774750 | 0.88 | KDM4E (0.68) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL26665270 | 0.85 | KDM4E (1.00) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL30656644 | 0.85 | KDM4E (0.77) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL26665250 | 0.85 | KDM4E (0.77) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL26665246 | 0.84 | KDM4E (0.78) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL28823005 | 0.83 | KDM4E (0.83) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL22594333 | 0.80 | KDM4E (0.78) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL26665245 | 0.80 | KDM4E (0.76) | KDM4ELMNATDP1SMN1; SMN2OPRK1 | |
| SCHEMBL30656643 | 0.80 | KDM4E (0.72) | KDM4ELMNATDP1SMN1; SMN2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023224371-A1 | NOVEL OXADIAZOLE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY DISEASES COMPRISING SAME | (주)셀로스바이오텍 | 2023-11-23 | — | — | WO | claimed |
| WO-2023224371-A1 | NOVEL OXADIAZOLE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY DISEASES COMPRISING SAME | (주)셀로스바이오텍 | 2023-11-23 | — | — | WO | disclosed |