Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.50 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126949 | 1.00 | GRIK1 (0.50) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27420986 | 0.86 | GRIK1 (0.50) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27708625 | 0.81 | GRIK1 (0.51) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL25822704 | 0.80 | GRIA1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29126950 | 0.79 | TSHR (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29127000 | 0.79 | LMNA (0.59) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30657598 | 0.79 | LMNA (0.59) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30657599 | 0.79 | TDP1 (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL30657595 | 0.79 | TSHR (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28038249 | 0.79 | TDP1 (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143104-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2023-12-01 | — | — | CN | claimed |
| CN-117143104-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2023-12-01 | — | — | CN | disclosed |