SCHEMBL30657883

SCHEMBL30657883

CS(=O)(=O)Oc1cccc(NC(=O)Nc2cccc(OS(=O)(=O)c3ccccc3)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.51
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA9 Q16790 3/20 0.51
MAPT P10636 3/20 0.51
LMNA P02545 3/20 0.49
MAPK1 P28482 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
FAAH O00519 2/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
MITF O75030 1/20 0.48
TSHR P16473 2/20 0.48
TP53 P04637 1/20 0.48
IDH1 O75874 1/20 0.47
GPR17 Q13304 1/20 0.46
ALOX15 P16050 1/20 0.46
ENPP3 O14638 1/20 0.45
ENPP1 P22413 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29620069 0.93 CA2 (0.57) CA2CA12CA1CA9MAPT
SCHEMBL22187323 0.93 CA2 (0.57) CA2CA12CA1CA9MAPT
SCHEMBL22446482 0.92 MAPT (0.60) CA2CA12CA1CA9MAPT
SCHEMBL22187133 0.90 GPR17 (0.53) CA2MAPTLMNAMAPK1MEN1
SCHEMBL30540129 0.90 GPR17 (0.53) CA2MAPTLMNAMAPK1MEN1
SCHEMBL22187308 0.89 TSHR (0.58) CA2CA12CA1CA9MAPT
SCHEMBL29673688 0.89 TSHR (0.58) CA2CA12CA1CA9MAPT
SCHEMBL22187158 0.88 GPR17 (0.54) CA2CA12CA1CA9MAPT
SCHEMBL30540135 0.88 GPR17 (0.54) CA2CA12CA1CA9MAPT
SCHEMBL22187134 0.88 CA2 (0.65) CA2CA12CA1CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117083182-A Thermosensitive recording layer forming liquid, thermosensitive recording medium, production method thereof, and image recording method 株式会社理光 2023-11-17 CN disclosed