Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.42 |
| ▸ | FEN1 | P39748 | 13/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91447 | 1.00 | GRM5 (0.54) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL21201805 | 0.90 | GRM5 (0.44) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL17430662 | 0.81 | GRM5 (0.36) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12462535 | 0.79 | GRM5 (0.54) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13114366 | 0.79 | GRM5 (0.54) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL18307148 | 0.79 | GRM5 (0.54) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL858890 | 0.79 | GRM5 (0.54) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12019744 | 0.78 | GRM5 (0.50) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL84582 | 0.78 | GRM5 (0.50) | GRM5ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12020144 | 0.78 | GRM5 (0.60) | GRM5ALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677738-A | Compounds and uses thereof | 福宏治疗公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4522280-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220219-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |