Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654031 | 1.00 | TTR (0.40) | TTRTSHRTPMTCTNNB1WNT3A | |
| SCHEMBL26653828 | 0.83 | ALDH1A1 (0.38) | TSHRNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL14907127 | 0.75 | TTR (0.44) | TTRTSHRTPMTNPC1RAB9A | |
| SCHEMBL26653676 | 0.73 | TTR (0.37) | TTRTSHRTPMTPLAUNOTUM | |
| SCHEMBL26654163 | 0.73 | CTNNB1 (0.57) | TSHRCTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL3959311 | 0.71 | TTR (0.47) | TTRTSHRTPMTNPC1RAB9A | |
| SCHEMBL7215155 | 0.68 | PARP1 (0.38) | MAPK8 | |
| SCHEMBL26653937 | 0.67 | ALDH1A1 (0.38) | CTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL7215187 | 0.67 | PARP1 (0.37) | TSHRCTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL3705853 | 0.65 | ALDH1A1 (0.53) | TTRTSHRTPMTCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522280-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220219-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |