Hydroxyprogesterone

Hydroxyprogesterone

SCHEMBL30657985

CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=[13CH][13C](=O)[13CH2]C[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 1.00
SHBG P04278 6/20 1.00
CYP2C19 P33261 5/20 1.00
SERPINA6 P08185 5/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
NR3C1 P04150 4/20 1.00
BLM P54132 4/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
MAPT P10636 2/20 1.00
ADORA3 P0DMS8 1/20 1.00
MAPK3 P27361 1/20 1.00
SLC6A3 Q01959 1/20 1.00
HIF1A Q16665 5/20 0.78
HSD17B10 Q99714 4/20 0.78
TSHR P16473 4/20 0.78
PMP22 Q01453 3/20 0.78
CYP3A4 P08684 2/20 0.78
ALDH1A1 P00352 3/20 0.74
PGR P06401 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyprogesterone SCHEMBL8068 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL18261234 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL265609 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL23456341 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL13558389 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL24287585 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL3931615 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL14523053 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL14546356 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2
Hydroxyprogesterone SCHEMBL27048177 1.00 LMNA (1.00) LMNASHBGCYP2C19SERPINA6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114705787-B Method for detecting 12 steroid hormone in dried blood spots based on derivatization 天津国科医疗科技发展有限公司 2024-08-27 CN claimed
CN-122017085-A Method for simultaneously detecting multiple steroid hormones in serum 北京大学第三医院(北京大学第三临床医学院) 2026-05-12 CN disclosed
CN-114705787-B Method for detecting 12 steroid hormone in dried blood spots based on derivatization 天津国科医疗科技发展有限公司 2024-08-27 CN disclosed
CN-117147739-A Free hormone detection method for converting ultrafiltration result into equilibrium dialysis result 合肥歆智医疗器械有限公司 2023-12-01 CN disclosed
CN-117147740-A Ultrafiltration-mass spectrometry method and kit for measuring free progestogen in blood 合肥歆智医疗器械有限公司 2023-12-01 CN disclosed