Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658112 | 1.00 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL24675338 | 1.00 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL24640560 | 0.90 | MEN1 (0.40) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL29274223 | 0.85 | MDM2 (0.41) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL30719996 | 0.85 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL29088953 | 0.82 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL24640582 | 0.82 | HDAC6 (0.42) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL29841730 | 0.82 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL30729648 | 0.82 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL24763586 | 0.81 | TIPARP (0.53) | HDAC6HDAC8TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083274-A | Fused ring heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-11-17 | — | — | CN | disclosed |