Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729618 | 0.88 | TIPARP (0.40) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL24764576 | 0.88 | TIPARP (0.54) | MEN1KMT2AHDAC6HDAC8TIPARP | |
| SCHEMBL24640582 | 0.87 | HDAC6 (0.42) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL29841730 | 0.85 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL24675338 | 0.85 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL30658112 | 0.85 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL30729648 | 0.85 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL29088953 | 0.85 | MEN1 (0.43) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL30658111 | 0.85 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 | |
| SCHEMBL24675215 | 0.84 | TIPARP (0.42) | MEN1KMT2AHDAC6HDAC8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430606-A | Sulfonamide PARP7 inhibitors | 山东轩竹医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |