Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | ADK | P55263 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15619623 | 0.80 | KDM4E (1.00) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL15620022 | 0.80 | MAPT (0.60) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL30658875 | 0.80 | MAPT (0.60) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL30658859 | 0.78 | KDM4E (0.40) | POLBKDM4EMAPTGSK3BADK | |
| SCHEMBL15620759 | 0.78 | KDM4E (0.40) | POLBKDM4EMAPTGSK3BADK | |
| SCHEMBL29851900 | 0.77 | KDM4E (0.59) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL30658886 | 0.77 | KDM4E (0.59) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL15621079 | 0.77 | KDM4E (0.59) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL15620032 | 0.76 | MAPT (0.67) | POLBKDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL15619911 | 0.76 | KDM4E (0.67) | POLBKDM4EMAPTCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818660-B | Beta-hydroxylase inhibitors for the treatment of cancer | 罗得岛医院 | 2023-09-12 | — | — | CN | disclosed |